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ADD1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human lung cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human ADD1
Abbre
ADD1
Synonyms
ADD A;ADD1;ADDA;ADDA;Adducin 1 (alpha);Alpha adducin;Alpha-adducin;Erythrocyte adducin alpha subunit;Erythrocyte adducin subunit alpha;MGC3339;MGC44427;OTTHUMP00000151163;OTTHUMP00000151164;OTTHUMP00000151165;OTTHUMP00000218664;OTTHUMP00000218665抗体
Swissprot
Cellular Localization
Cytoplasm>cytoskeleton. Cell membrane.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Signal Transduction; Tags and Cell Markers
Conjugation
Unconjugated
Background
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ADD1 Polyclonal Antibody at dilution 1:50


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