本公司产品仅供体外研究使用,不用于临床诊断

AFP Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:E-AB-40293

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms Alpha-fetoprotein,Alpha-1-fetoprotein,Alpha-fetoglobulin,Afp
    Swissprot P02772
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant Mouse Afp protein expressed by E.coli
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:1000;IHC,,1:200-1:500;IF,,1:100-1:200;
    Concentration 1.1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted
    Tissue specificity Plasma.Highest expression level in embryo.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
    Background This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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