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AKAP12 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human brain,Human lung cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human AKAP12
Abbre
AKAP12
Synonyms
A kinase (PRKA) anchor protein (gravin) 12;A kinase Anchor Protein 12;A kinase anchor protein 250kDa;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;AKA12;AKAP 12;AKAP 250;AKAP-12;Akap12;AKAP250;DKFZp686M0430;DKFZp686O0331;FLJ20945;FLJ97621;Gercelin;Gravin;Kinase scaffold protein gravin;Myasthenia gravis autoantigen;Myasthenia gravis autoantigen gravin;OTTHUMP00000017426;OTTHUMP00000017427;Src-Suppressed C Kinase Substrate;Srcs5;SSeCKS;Tsga12抗体
Swissprot
Cellular Localization
Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. May be part of the cortical cytoskeleton.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Neuroscience; Signal Transduction
Conjugation
Unconjugated
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Immunohistochemistry of paraffin-embedded Human brain tissue using AKAP12 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using AKAP12 Polyclonal Antibody at dilution 1:40


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