AKAP12 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human brain,Human lung cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human AKAP12 |
Abbre | AKAP12 |
Synonyms | A kinase (PRKA) anchor protein (gravin) 12;A kinase Anchor Protein 12;A kinase anchor protein 250kDa;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;AKA12;AKAP 12;AKAP 250;AKAP-12;Akap12;AKAP250;DKFZp686M0430;DKFZp686O0331;FLJ20945;FLJ97621;Gercelin;Gravin;Kinase scaffold protein gravin;Myasthenia gravis autoantigen;Myasthenia gravis autoantigen gravin;OTTHUMP00000017426;OTTHUMP00000017427;Src-Suppressed C Kinase Substrate;Srcs5;SSeCKS;Tsga12抗体 |
Swissprot | |
Cellular Localization | Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. May be part of the cortical cytoskeleton. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Background | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Immunohistochemistry of paraffin-embedded Human brain tissue using AKAP12 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using AKAP12 Polyclonal Antibody at dilution 1:40
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |