AMPK alpha1 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p
| Verified Samples |
Verified Samples in WB:Hela,293T,3T3,PC12 Verified Samples in IHC:Mouse colon |
| Dilution | WB 1:1000-2000;IHC 1:50-100 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | AMPK α1 |
| Synonyms | 5 AMP activated protein kinase alpha 1catalytic subunit;5 AMP activated protein kinase catalytic alpha 1 chain;5' AMP activated protein kinase catalytic subunit alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AAPK1;AAPK1;ACACA kinase;acetyl CoA carboxylase kinase;AI194361;AI450832;AL024255;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase;catalytic;alpha -1;AMPK 1;AMPK alpha 1;AMPK alpha 1 chain;AMPK;AMPK subunit alpha-1;AMPK1;AMPKa1;AMPKalpha1;C130083N04Rik;cb116;EC 2.7.11.1;HMG CoA reductase kinase;HMGCR kinase;hormone sensitive lipase kinase;Hydroxymethylglutaryl CoA reductase kinase;im:7154392;kinase AMPK alpha1;MGC33776;MGC57364;OTTHUMP00000161795;OTTHUMP00000161796;PRKAA 1;PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit;SNF1-like protein AMPK;SNF1A;Tau protein kinase PRKAA1;wu:fa94c10抗体 |
| Swissprot | |
| Observed MW | 63kDa |
| Cellular Localization | Cytosol,Nucleus,nuclear speck,nucleoplasm,nucleus,Plasma Membrane,apical plasma membrane,Other locations:cytoplasm,intracellular,nucleotide-activated protein kinase complex |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction |
| Clone No. | Clone:6B6 |
| Conjugation | Unconjugated |
| Background | Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
Western Blot analysis of 1) Hela, 2) 293T, 3) 3T3, 4) PC-12 cells using AMPK alpha1 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Mouse colon tissue using AMPK alpha1 Monoclonal Antibody at dilution of 1:200.
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
