ARHGDIB Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:293T,A431,HepG2 Verified Samples in IHC:Human esophagus cancer,Human gastric cancer |
| Dilution | WB 1:500-1:2000;IHC 1:25-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human ARHGDIB |
| Abbre | ARHGDIB |
| Synonyms | Arhgdib;D4;D4 GDP dissociation inhibitor;GDIA 2;GDIA2;GDID 4;GDID4;GDIR2;GDP dissociation inhibitor D4;LY GDI;Ly-GDI;LYGDI;MGC108926;RAP1GN1;Rho GDI 2;Rho GDI beta;Rho GDI2;Rho GDP dissociation inhibitor (GDI) beta;Rho GDP dissociation inhibitor 2;Rho GDP dissociation inhibitor beta;Rho GDP-dissociation inhibitor 2;Rho-GDI beta;RhoGDI2抗体 |
| Swissprot | |
| Calculated MW | 23 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm, cytosol. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Signal Transduction |
| Conjugation | Unconjugated |
| Background | ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them.
It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer. |
Western blot analysis of 293T A431 and HepG2 cell lysates using ARHGDIB Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
