ATF1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Hela,HepG2,RAW264.7,Mouse kidney,Mouse colon,Mouse brain,Rat kidney,Rat colon,Rat brain |
| Dilution | WB 1:500-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ATF1 |
| Abbre | ATF1 |
| Synonyms | Activating transcription factor 1;ATF 1;atf1;ATF1 EWS fusion gene;ATF1 FUS fusion gene;ATF1;cAMP dependent transcription factor 1;cAMP-dependent transcription factor ATF-1;Cyclic AMP dependent transcription factor ATF 1;Cyclic AMP dependent transcription factor ATF1;Cyclic AMP-dependent transcription factor ATF-1;EWS AFT1;FUS ATF 1;FUS/ATF 1;Protein TREB36;RNA binding protein activating transcription factor 1 fusion protein;TREB 36;TREB36;TREB36 protein抗体 |
| Swissprot | |
| Calculated MW | 29kDa |
| Observed MW | 29kDa |
| Cellular Localization | Nucleus |
| Concentration | 0.59 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. |
Western Blot analysis of various samples using ATF1 Polyclonal Antibody at dilution of 1:1000.
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
