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BCL2L2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:HL-60
Verified Samples in IHC:Human liver cancer
Dilution
WB 1:500-1:2000;IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human BCL2L2
Abbre
BCL2L2
Synonyms
Apoptosis regulator BCL W;Apoptosis regulator Bcl-W;B2CL2;BCL 2 Like 2;Bcl 2 like 2 protein;Bcl 2L2;BCL W;Bcl-2-like protein 2;Bcl2 L2;BCL2 like 2;BCL2 like 2 protein;Bcl2-L-2;Bcl2l2;BCLW;KIAA0271;PPP1R51;Protein phosphatase 1 regulatory subunit 51抗体
Swissprot
Calculated MW
21 kDa
Observed MW
Refer to figures
Cellular Localization
Mitochondrion membrane. Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
Concentration
0.8 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cell Biology
Conjugation
Unconjugated
Background
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
Western blot analysis of HL-60 cell lysate using BCL2L2 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using BCL2L2 Polyclonal Antibody at dilution of 1:40(×200)


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