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BLNK Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:LoVo
Verified Samples in IHC:Human thyroid cancer,Human gastric cancer
Dilution
WB 1:500-1:2000;IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human BLNK
Abbre
BLNK
Synonyms
AGM4;B cell adapter containing SH2 domain protein;B cell adapter containing Src homology 2 domain protein;B cell adaptor containing SH2 domain;B cell linker;B cell linker protein;B cell-specific adaptor protein;B-cell activation;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;B-cell linker protein;BASH;Bca;BLNK;BLNK s;BLNK;Cytoplasmic adapter protein;Ly 57;Ly57;Lymphocyte antigen 57;Lyw 57;Lyw57;MGC111051;SH2 domain-containing leukocyte protein;65-KD;SLP 65;SLP-65;SLP65;Src homology [SH2] domain-containing leukocyte protein of 65 kD;Src homology 2 domain containing leukocyte protein of 65 kDa;Src homology 2 domain-containing leukocyte protein of 65 kDa抗体
Swissprot
Calculated MW
50 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasm. Cell membrane. BCR activation results in the translocation to membrane fraction.
Concentration
1.02 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Immunology; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
Western blot analysis of LOVO cell lysate using BLNK Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using BLNK Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using BLNK Polyclonal Antibody at dilution of 1:40(×200)


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