BLNK Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human lung cancer,Human colon cancer |
Dilution | WB 1:500-1:2000;IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human BLNK |
Abbre | BLNK |
Synonyms | AGM4;B cell adapter containing SH2 domain protein;B cell adapter containing Src homology 2 domain protein;B cell adaptor containing SH2 domain;B cell linker;B cell linker protein;B cell-specific adaptor protein;B-cell activation;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;B-cell linker protein;BASH;Bca;BLNK;BLNK s;BLNK;Cytoplasmic adapter protein;Ly 57;Ly57;Lymphocyte antigen 57;Lyw 57;Lyw57;MGC111051;SH2 domain-containing leukocyte protein;65-KD;SLP 65;SLP-65;SLP65;Src homology [SH2] domain-containing leukocyte protein of 65 kD;Src homology 2 domain containing leukocyte protein of 65 kDa;Src homology 2 domain-containing leukocyte protein of 65 kDa抗体 |
Swissprot | |
Calculated MW | 50kDa |
Cellular Localization | Cytoplasm. Cell membrane. BCR activation results in the translocation to membrane fraction. |
Concentration | 0.6 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Immunology; Signal transduction |
Conjugation | Unconjugated |
Background | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. |
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using BLNK Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using BLNK Polyclonal Antibody at dilution 1:50
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |