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c-Fos Monoclonal Antibody

Price: ¥2310 ¥1420 ¥580

Size:
120μL 60μL 20μL
  • 宿主: Mouse
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC-p
Verified Samples
Verified Samples in WB:Hela,293T,Mouse brain,Rat brain
Verified Samples in IHC:Human breast carcinoma
Dilution
WB 1:500-1:2000;IHC 1:100-1:300
Clonality
Monoclonal
Isotype
IgG
Immunogen
Recombinant Protein
Abbre
c-Fos
Synonyms
Activator protein 1;AP 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog;FBJ Osteosarcoma Virus;FOS;FOS protein;FOS;G0 G1 switch regulatory protein 7;G0/G1 switch regulatory protein 7;G0S7;Oncogene FOS;p55;proto oncogene c Fos;Proto oncogene protein c fos;Proto-oncogene c-Fos;v fos FBJ murine osteosarcoma viral oncogene homolog抗体
Swissprot
Observed MW
62kDa
Cellular Localization
Nucleus.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method
Protein A purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling; Neuroscience
Clone No.
6A3
Conjugation
Unconjugated
Background
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse brain, 4) Rat brain using c-Fos Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using c-Fos Monoclonal Antibody at dilution of 1:200.


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