CD54 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Raji,HUVEC Verified Samples in IHC:Human gastric cancer,Human liver cancer |
Dilution | WB 1:1000-1:5000;IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human ICAM1 |
Abbre | ICAM1 |
Synonyms | Antigen identified by monoclonal BB2;BB 2;BB2;CD 54;CD_antigen=CD54;CD54;Cell surface glycoprotein P3.58;Human rhinovirus receptor;ICAM 1;ICAM-1;ICAM1;ICAM1;intercellular adhesion molecule 1 (CD54);human rhinovirus receptor;Intercellular adhesion molecule 1;Major group rhinovirus receptor;MALA 2;MALA2;MyD 10;MyD10;P3.58;Surface antigen of activated B cells;BB2抗体 |
Swissprot | |
Calculated MW | 58kDa |
Cellular Localization | Membrane |
Concentration | 0.6 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cardiovascular; Immunology; Stem Cells |
Conjugation | Unconjugated |
Background | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Western Blot analysis of Raji and huvec cell using CD54 Polyclonal Antibody at dilution of 1:1150
Immunohistochemistry of paraffin-embedded Human gastic cancer using CD54 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer using CD54 Polyclonal Antibody at dilution of 1:50
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