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CDC42BPA Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human lung cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CDC42BPA
Abbre
CDC42BPA
Synonyms
A930014J19Rik;CDC42 binding protein kinase alpha (DMPK like);CDC42 binding protein kinase alpha;CDC42 binding protein kinase alpha dmpk like;CDC42 binding protein kinase beta;CDC42-binding protein kinase alpha;CDC42BPA;DKFZp686L1738;DKFZp686P1738;DMPK like;DMPK-like alpha;FLJ23347;KIAA0451;MGC189823;MRCK alpha;mrck;mrcka;MRCKA;Myotonic dystrophy kinase related CDC42 binding protein kinase alpha;Myotonic dystrophy kinase-related CDC42-binding kinase alpha;Myotonic dystrophy protein kinase-like alpha;OTTHUMP00000035727;OTTHUMP00000035728;OTTHUMP00000035729;OTTHUMP00000035730;pk428;RP5-1087E8.4;Ser thr protein kinase PK428;Ser thr protein kinase related to the myotonic dystrophy protein kinase;Serine/threonine protein kinase MRCK alpha;Serine/threonine-protein kinase MRCK alpha抗体
Swissprot
Cellular Localization
Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
Concentration
0.8 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CDC42BPA Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CDC42BPA Polyclonal Antibody at dilution of 1:60(×200)


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