CDK4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human stomach cancer,Human breast,Human colon,Rat ovary,Rat testis |
| Dilution | IHC 1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CDK4 |
| Abbre | CDK4 |
| Synonyms | Cdk 4;cdk4;CDK4 protein;CDK4;Cell division kinase 4;Cell division protein kinase 4;CMM 3;CMM3;Crk3;Cyclin dependent kinase 4;Cyclin-dependent kinase 4;Melanoma cutaneous malignant 3;MGC14458;p34 cdk4;PSK J3;PSK-J3抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Membrane, Nucleus |
| Concentration | 210 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. |
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CDK4 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded human breast using CDK4 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded human colon using CDK4 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded rat ovary using CDK4 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded rat testis using CDK4 Polyclonal Antibody at dilution of 1:100.
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
