CFL1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB
| Verified Samples |
Verified Samples in WB:A431,Jurkat |
| Dilution | WB 1:500-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant human Homeobox protein Cofilin-1 protein |
| Abbre | Cofilin-1 |
| Synonyms | 18 kDa phosphoprotein;CFL 1;CFL;CFL1;COF1;Cofilin 1;Cofilin 1 non muscle;Cofilin;Cofilin non muscle isoform;Cofilin-1;epididymis secretory protein Li 15;HEL-S-15;non-muscle isoform;p18抗体 |
| Swissprot | |
| Calculated MW | 17 kDa |
| Observed MW | 17 kDa |
| Cellular Localization | Nucleus matrix. Cytoplasm>cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide. |
| Concentration | 2 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Neuroscience; Signal Transduction |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Western Blot analysis of A431 and Jurkat cells using CFL1 Polyclonal Antibody at dilution of 1:600
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
