CHOP Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colon,Human stomach cancer,Mouse brain,Rat brain |
| Dilution | IHC 1:100-500 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CHOP |
| Abbre | CHOP |
| Synonyms | C/EBP homologous protein;C/EBP Homology Protein;C/EBP zeta;C/EBP-homologous protein 10;C/EBP-homologous protein;CCAAT/enhancer binding protein homologous protein;CEBPZ;CHOP 10;CHOP;CHOP-10;CHOP10;DDIT 3;DDIT-3;Ddit3;DDIT3;DNA Damage Inducible Transcript 3;DNA damage-inducible transcript 3 protein;GADD 153;GADD153;Growth Arrest and DNA Damage Inducible Protein 153;Growth arrest and DNA damage inducible protein GADD153;Growth arrest and DNA damage-inducible protein GADD153;MGC4154抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Nucleus |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Metabolism; Developmental Biology; Stem Cells |
| Conjugation | Unconjugated |
| Background | CHOP,also known as GADD153 or DDIT3,is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins,CHOP is significantly induced by ER stress,deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma. |
Immunohistochemistry analysis of paraffin-embedded human colon using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse brain using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using CHOP Polyclonal Antibody at dilution of 1:300.
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