Chromogranin A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40339
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | beta Granin,betagranin (N-terminal fragment of chromogranin A),catestatin,CgA,CHG A,Chga,chromofungin,Chromogranin A,Chromogranin A parathyroid secretory protein 1,Chromogranin A precursor,ChromograninA,CMGA,ER-37,Pancreastatin,Parastatin,Parathyroid secretory protein 1,Pituitary secretory protein I,Secretory protein I,SP I,SP-I,SP1,SPI,Vasostatin,Vasostatin I,Vasostatin II,Chromogranin A抗体 |
| Swissprot | P26339 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant Mouse Chromogranin-A protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000;IHC,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic vesicle, Membrane, Secreted |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin,pancreastatin,catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) ,and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors. |
Images
Western Blot analysis of PC-3 cells using Chromogranin A Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human duodenum using Chromogranin A Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Mouse small intestine using Chromogranin A Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Mouse pancreas using Chromogranin A Polyclonal Antibody at dilution of 1:200
