CREBZF Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Mouse brain,PC-3 Verified Samples in IHC:Human liver cancer |
Dilution | WB 1:500-1:2000;IHC 1:25-1:100 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human CREBZF |
Abbre | CREBZF |
Synonyms | 1110034C16Rik;6330417B10Rik;AI225749;AI606244;CREB/ATF bZIP transcription factor;Crebzf;FLJ94018;HCF-binding transcription factor Zhangfei;Host cell factor-binding transcription factor Zhangfei;LAZip;LAZipII;SHP-interacting leucine zipper protein;SMILE;ZF;ZHANG抗体 |
Swissprot | |
Calculated MW | 37 kDa |
Observed MW | Refer to figures |
Cellular Localization | Nucleus. Colocalizes at punctate nuclear structures with CREB3 and HCFC1. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF). Luman activates promoters containing cAMP or unfolded protein response elements (UPRE). Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain. |
Western blot analysis of Mouse brain tissue PC3 cells using CREBZF Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CREBZF Polyclonal Antibody at dilution of 1:50(×200)
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |