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CREBZF Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Mouse brain,PC-3
Verified Samples in IHC:Human liver cancer
Dilution
WB 1:500-1:2000;IHC 1:25-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CREBZF
Abbre
CREBZF
Synonyms
1110034C16Rik;6330417B10Rik;AI225749;AI606244;CREB/ATF bZIP transcription factor;Crebzf;FLJ94018;HCF-binding transcription factor Zhangfei;Host cell factor-binding transcription factor Zhangfei;LAZip;LAZipII;SHP-interacting leucine zipper protein;SMILE;ZF;ZHANG抗体
Swissprot
Calculated MW
37 kDa
Observed MW
Refer to figures
Cellular Localization
Nucleus. Colocalizes at punctate nuclear structures with CREB3 and HCFC1.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF). Luman activates promoters containing cAMP or unfolded protein response elements (UPRE). Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain.
Western blot analysis of Mouse brain tissue PC3 cells using CREBZF Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CREBZF Polyclonal Antibody at dilution of 1:50(×200)


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