ER alpha Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human brain,Human thyroid cancer |
| Dilution | IHC 1:100-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human ESR1 |
| Abbre | ESR1 |
| Synonyms | DKFZp686N23123;ER alpha;ER;ER-alpha;Era;ESR;ESR1;ESR1;ESRA;Estradiol receptor;Estrogen nuclear receptor alpha;Estrogen receptor 1;Estrogen receptor alpha 3*;4;5;6;7*/822 isoform;Estrogen receptor alpha;Estrogen receptor alpha delta 3*;4;5;6;7*;8*/941 isoform;Estrogen receptor alpha delta 3*;4;5;6;7*/819 2 isoform;Estrogen receptor alpha delta 4 +49 isoform;Estrogen receptor alpha delta 4*;5;6;7*/654 isoform;Estrogen receptor alpha delta 4*;5;6;7;8*/901 isoform;Estrogen receptor alpha E1 E2 1 2;Estrogen receptor alpha E1 N2 E2 1 2;Estrogen receptor;ESTRR;NR3A1;Nuclear receptor subfamily 3 group A member 1抗体 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Cell membrane. A minor fraction is associated with the inner membrane and Nucleus. Cytoplasm. Cell membrane. Associated with the inner membrane via palmitoylation. |
| Concentration | 0.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. |
Immunohistochemistry of paraffin-embedded Human brain tissue using ER alpha Polyclonal Antibody at dilution 1:76
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ER alpha Polyclonal Antibody at dilution 1:76
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
