FGR Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colorectal cancer,Human cervical cancer |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human FGR |
| Abbre | FGR |
| Synonyms | c fgr;c fgr protooncogene;c src 2 proto oncogene;c src2;Fgr;FGR;FLJ43153;Gardner Rasheed feline sarcoma viral (v fgr);Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog;Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog;MGC75096;p55 c fgr protein;P55 FGR;P55-FGR;p55c fgr;p58-Fgr;p58c fgr;p58c-Fgr;Proto oncogene c Fgr;Proto oncogene tyrosine protein kinase FGR;Proto-oncogene c-Fgr;SRC 2;SRC2;Tyrosine protein kinase Fgr;Tyrosine-protein kinase Fgr抗体 |
| Swissprot | |
| Cellular Localization | Cell membrane. Cell membrane. Cell projection>ruffle membrane. Cytoplasm>cytosol. Cytoplasm>cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts. |
| Concentration | 2.04 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using FGR Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FGR Polyclonal Antibody at dilution of 1:70(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
