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FZD8 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer,Human liver cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human FZD8
Abbre
FZD8
Synonyms
Frizzled 8 seven transmembrane spanning receptor;frizzled 8;seven transmembrane spanning receptor;Frizzled family receptor 8;frizzled homolog 8 (Drosophila);Frizzled homolog 8;Frizzled-8;FZ 8;Fz-8;FZ8;FZD 8;FZD8;FZD8;hFZ 8;hFz8;HGNC4046;Homolog of Drosophila Frizzled 8抗体
Swissprot
Cellular Localization
Membrane. Golgi apparatus. Cell membrane. Colocalizes with GOPC at the Golgi apparatus.
Concentration
0.2 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Signal Transduction; Stem Cells
Conjugation
Unconjugated
Background
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using FZD8 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FZD8 Polyclonal Antibody at dilution 1:50


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