GTPase Kras Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Hela,Mouse heart,Rat heart,Rat skeletal muscle |
| Dilution | WB 1:1000-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human KRAS protein expressed by E.coli. |
| Abbre | KRAS |
| Synonyms | KRAS;KRAS2;RASK2;GTPase Kras;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;GTPase Kras抗体 |
| Swissprot | |
| Calculated MW | 21 kDa |
| Observed MW | 21 kDa |
| Cellular Localization | Cell membrane, Cytoplasm, cytosol |
| Concentration | 2.5mg/ml |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide,50% glycerol,pH 7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Signal Transduction |
| Conjugation | Unconjugated |
| Background | KRAS,also called p21,is a member of the Ras superfamily of proteins. It is located on human chromosome 12,and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family,the KRAS protein is a GTPase,and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies,including lung adenocarcinoma,mucinous adenoma,ductal carcinoma of the pancreas and colorectal carcinoma. |
Western blotting with anti-KRAS polyclonal Antibody at dilution of 1:1000. Lane 1: Hela cell lysates, lane 2: Mouse heart lysate.
Western blotting with anti-KRAS polyclonal Antibody at dilution of 1:1000. Lane 1: Rat heart lysates, lane 2:Rat skeletal muscle lysate.
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| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
