HIST1H3A Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:293T,NIH/3T3,Mouse liver,HUVEC Verified Samples in IHC:Human liver cancer,Human esophagus cancer |
Dilution | WB 1:500-1:2000;IHC 1:25-1:100 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human HIST1H3A |
Abbre | HIST1H3A |
Synonyms | H3 histone family;member A;H3/A;H31;H3FA;Hist1h3a;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E;HIST1H3F;HIST1H3G;HIST1H3H;HIST1H3I;HIST1H3J;histone 1;H3a;Histone cluster 1;H3a;Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l抗体 |
Swissprot | |
Calculated MW | 15 kDa |
Observed MW | Refer to figures |
Cellular Localization | Nucleus. Chromosome. |
Concentration | 0.5 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. |
Western blot analysis of 293T and NIH/3T3 cell Mouse liver tissue HUVEC cell lysates using HIST1H3A Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HIST1H3A Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HIST1H3A Polyclonal Antibody at dilution of 1:30(×200)
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