IL6R Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40344
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CD 126,CD126,CD126 antigen,gp80,IL 6R 1,IL 6R alpha,IL 6R,IL-6 receptor alpha chain,IL-6 receptor subunit alpha,IL-6R 1,IL-6R subunit alpha,IL-6R-alpha,IL-6RA,IL6Q,Il6r,IL6RA,IL6RA,IL6RQ,Interleukin 6 receptor,interleukin 6 receptor,alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80,MGC30256,IL6R抗体 |
| Swissprot | P08887 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Human Interleukin-6 receptor subunit alpha protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:2000;IHC,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Membrane, Secreted |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |
Images
Western Blot analysis of Rat liver, Mouse spleen and Mouse liver using IL6R Polyclonal Antibody at dilution of 1:2000
Western Blot analysis of Rat spleen using IL6R Polyclonal Antibody at dilution of 1:2000
Western Blot analysis of Jurkat and Hela Cells using IL6R Polyclonal Antibody at dilution of 1:2000
Immunohistochemistry of paraffin-embedded Mouse spleen using IL6R Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat spleen using IL6R Polyclonal Antibody at dilution of 1:200
