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ISCU Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:Mouse lung
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human ISCU
Abbre
ISCU
Synonyms
2310020H20Rik;HML;hnifU;Iron sulfur cluster assembly enzyme ISCU mitochondrial;Iron sulfur cluster scaffold homolog (E. coli);Iron sulfur cluster scaffold homolog;Iron-sulfur cluster assembly enzyme ISCU;Iscu;IscU iron sulfur cluster scaffold homolog;ISCU;ISU2;MGC74517;mitochondrial;NIFU;NifU like N terminal domain containing;NifU like N terminal domain containing protein;NifU like protein;NifU-like N-terminal domain-containing protein;NifU-like protein;NIFUN;Nitrogen fixation cluster like;OTTHUMP00000238760;OTTHUMP00000238761;OTTHUMP00000238762;OTTHUMP00000238764;OTTHUMP00000238765抗体
Swissprot
Calculated MW
18 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasm. Nucleus and Mitochondrion.
Concentration
0.96 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Metabolism; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Western blot analysis of Mouse lung tissue lysate using ISCU Polyclonal Antibody at dilution of 1:400
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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