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LDHA Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70210

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms Cell proliferation-inducing gene 19 protein,L lactate dehydrogenase A chain,Lactate dehydrogenase A,LDH A,LDH M,LDH muscle subunit,LDH1,LDH5,LDHA,PIG 19,PIG19,Renal carcinoma antigen NY-REN-59,LDHA抗体
    Swissprot P00338,P06151,P04642
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse LDHA
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:2000;IHC,,1:400-1:1000;
    Concentration 0.6 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm
    Tissue specificity Highest expression level in left coronary artery
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
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