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LPIN1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:NIH/3T3,K562,HepG2
Verified Samples in IHC:Human gastric cancer
Dilution
WB 1:500-1:2000;IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human LPIN1
Abbre
LPIN1
Synonyms
EC=3.1.3.4;KIAA0188 ;Lipin-1;Lpin1;LPIN1;PAP1;Phosphatidate phosphatase LPIN1抗体
Swissprot
Calculated MW
99 kDa
Observed MW
Refer to figures
Cellular Localization
Nucleus. Cytoplasm>cytosol. Endoplasmic reticulum membrane.
Concentration
1.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cell Biology; Cardiovascular; Metabolism; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
Western blot analysis of NIH/3T3 K562 and HepG2 cell lysates using LPIN1 Polyclonal Antibody at dilution of 1:850
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using LPIN1 Polyclonal Antibody at dilution of 1:60(×200)


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