LRPAP1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:293T,Human fetal kidney Verified Samples in IHC:Human colon cancer |
| Dilution | WB 1:500-1:2000;IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human LRPAP1 |
| Abbre | LRPAP1 |
| Synonyms | 39 kDa receptor-associated protein;A2MRAP;A2RAP;Alpha 2 macroglobulin receptor associated protein;Alpha 2 MRAP;Alpha-2-macroglobulin receptor-associated protein;Alpha-2-MRAP;AMRP;HBP44;Lipoprotein receptor associated protein;Low density lipoprotein receptor related protein associated protein 1;Low density lipoprotein receptor-related protein-associated protein 1;Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein;Low density lipoprotein related protein associated protein 1;low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1);Lrpap1;MGC138272;MRAP;MYP23;RAP抗体 |
| Swissprot | |
| Calculated MW | 41kDa |
| Cellular Localization | Endoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Metabolism; Signal Transduction |
| Conjugation | Unconjugated |
| Background | Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. |
Western Blot analysis of 293T cell and fetal kidney tissue using LRPAP1 Polyclonal Antibody at dilution of 1:1600
Immunohistochemistry of paraffin-embedded Human colon cancer using LRPAP1 Polyclonal Antibody at dilution of 1:100
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
