MAPK8 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:K562,Hela |
| Dilution | WB 1:1000-1:5000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human MAPK8 |
| Abbre | MAPK8 |
| Synonyms | AI849689;c Jun N terminal kinase 1;C-JUN kinase 1;c-Jun N-terminal kinase 1;EC 2.7.11.24;JNK 1;JNK;JNK-46;JNK1A2;JNK21B1/2;MAP kinase 8;MAPK 8;mapk8;Mitogen activated protein kinase 8;Mitogen-activated protein kinase 8;MK08;p54 gamma;Prkm8;Protein kinase JNK1;Protein kinase;mitogen-activated;8;SAPK 1;SAPK gamma;SAPK1;Stress-activated protein kinase 1;Stress-activated protein kinase JNK1抗体 |
| Swissprot | |
| Calculated MW | 48 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytosol,Mitochondrion,Nucleus,nucleoplasm,nucleus,Other locations:axon,basal dendrite,cytoplasm,neuron projection |
| Concentration | 1.9 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Immunology; Signal Transduction |
| Conjugation | Unconjugated |
| Background | MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot. |
Western blot analysis of K562 and hela cell using MAPK8 Polyclonal Antibody at dilution of 1:600
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
