MAPKAPK3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colorectal cancer,Human brain |
| Dilution | IHC 1:100-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human MAPKAPK3 |
| Abbre | MAPKAPK3 |
| Synonyms | 3pK;anti MAPKAPK3;Chromosome 3p kinase;EC 2.7.11.1;MAP kinase-activated protein kinase 3;MAPK activated protein kinase 3;MAPK-activated protein kinase 3;MAPK3;MAPKAP;MAPKAP kinase 3;MAPKAP-K3;MAPKAP3;MAPKAPK 3;MAPKAPK-3;Mapkapk3;MAPKAPK3;Mitogen activated protein kinase activated protein kinase 3;Mitogen activated protein kinase activated protein kinase;MK-3抗体 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Predominantly located in the nucleus, when activated it translocates to the cytoplasm. |
| Concentration | 1.4 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. |
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using MAPKAPK3 Polyclonal Antibody at dilution of 1:95(×200)
Immunohistochemistry of paraffin-embedded Human brain tissue using MAPKAPK3 Polyclonal Antibody at dilution of 1:95(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
