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MARK2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:A431,Raji
Verified Samples in IHC:Human liver cancer
Dilution
WB 1:500-1:2000;IHC 1:10-1:50
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human MARK2
Abbre
MARK2
Synonyms
ELKL motif kinase 1;ELKL motif kinase;EMK-1;EMK1;MAP/microtubule affinity regulating kinase 2;MAP/microtubule affinity-regulating kinase 2;Mark2;MARK2;MGC99619;PAR 1;Par 1b;PAR1 homolog;Par1b;Ser/Thr protein kinase PAR 1B;Serine/threonine protein kinase EMK;Serine/threonine protein kinase MARK2;Serine/threonine-protein kinase MARK2抗体
Swissprot
Calculated MW
88 kDa
Observed MW
Refer to figures
Cellular Localization
Cell membrane. Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Western blot analysis of A431 and Raji cell lysates using MARK2 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MARK2 Polyclonal Antibody at dilution of 1:25(×200)


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