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MFN2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC-p
Verified Samples
Verified Samples in WB:HUVEC
Dilution
WB 1:500-1:2000;IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human Mfn2.
Abbre
Mfn2
Synonyms
CMT2A;CMT2A2;CPRP 1;CPRP1;EC 3.6.5.-;Fzo;HSG;hyperplasia suppressor gene;Hypertension related protein 1;KIAA0214;MARF;MFN 2;Mfn2;MFN2;Mitochondrial assembly regulatory factor;Mitofusin-2;Mitofusin2;Transmembrane GTPase MFN2抗体
Swissprot
Calculated MW
86kDa
Observed MW
86kDa
Cellular Localization
Mitochondrion outer membrane. Colocalizes with BAX during apoptosis.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Tags and Cell Markers
Conjugation
Unconjugated
Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Western Blot analysis of HuvEc cells using Mfn2 Polyclonal Antibody at dilution of 1:1000.


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