MITF Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Jurkat,HeLa,K562,Mouse kidney |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein of human MITF (NP_937801.1). |
| Abbre | MITF |
| Synonyms | MITF;CMM8;COMMAD;MI;WS2;WS2A;bHLHe32抗体 |
| Swissprot | |
| Calculated MW | 40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa |
| Observed MW | 65kDa |
| Cellular Localization | Nucleus. |
| Concentration | 1mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Immunology |
| Conjugation | Unconjugated |
| Background | This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Western blot analysis of extracts of various cell lines using MITF Polyclonal Antibody at dilution of 1:1000.
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Chemical induced pathognomonic features observed in human vitiligo are mediated through miR-2909 RNomics pathway
IF: 3.681Journal：JOURNAL OF DERMATOLOGICAL SCIENCE
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