NFATC2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Human brain |
| Dilution | WB 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human NFATC2 |
| Abbre | NFATC2 |
| Synonyms | AI607462;cytoplasmic 2;KIAA0611;NF ATc2;NF ATp;NF-ATc2;NF-ATp;NFAC2;NFAT 1;NFAT pre existing subunit;NFAT pre-existing subunit;NFAT transcription complex;preexisting component;NFAT1;NFAT1-D;NFATc2;NFATp;Nuclear factor of activated T cells cytoplasmic 2;Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2;Nuclear factor of activated T cells pre-existing component;Nuclear factor of activated T cells;preexisting component;Nuclear factor of activated T-cells;Preexisting nuclear factor of activated T cells 2;T cell transcription factor NFAT 1;T-cell transcription factor NFAT1抗体 |
| Swissprot | |
| Calculated MW | 98kDa |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription. |
| Concentration | 0.7 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Immunology; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
Western Blot analysis of Human fetal brain tissue using NFATC2 Polyclonal Antibody at dilution of 1:650
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
