NFKB1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human gastric cancer,Human brain |
| Dilution | IHC 1:50-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human NFKB1 |
| Abbre | NFKB1 |
| Synonyms | DKFZp686C01211;DNA binding factor KBF1;DNA binding factor KBF1 EBP1;DNA-binding factor KBF1;EBP 1;EBP-1;EBP1;KBF1;MGC54151;nf b;NF kappa B;NF kappaB;NF kappabeta;NF kB1;NFkappaB;NFKB 1;NFKB p105;NFKB p50;Nfkb1;NFKB1;Nuclear factor kappa B DNA binding subunit;Nuclear factor kappa-B;subunit 1;Nuclear factor NF kappa B p105 subunit;Nuclear factor NF kappa B p50 subunit;Nuclear factor NF-kappa-B p50 subunit;Nuclear factor of kappa light chain gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;p105;p50;p84/NF-kappa-B1 p98;Transcription factor NFKB1抗体 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor. |
| Concentration | 1.38 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Immunology; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. |
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NFKB1 Polyclonal Antibody at dilution of 1:80(×200)
Immunohistochemistry of paraffin-embedded Human brain tissue using NFKB1 Polyclonal Antibody at dilution of 1:80(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
