NOS1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70065
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 2310005C01Rik,BNOS,Constitutive NOS,EC 1.14.13.39,IHPS 1,IHPS1,N-NOS,NC-NOS,neuronal Nitric Oxide Synthase,Neuronal NOS,Nitric oxide synthase,neuronal,included,Nitric oxide synthase 1 (neuronal),Nitric oxide synthase 1,Nitric oxide synthase,brain,Nitric oxide synthase,penile neuronal,included,NNOS,NO,NOS 1,NOS,NOS type I,NOS-I,NOS1,NOS1,Peptidyl-cysteine S-nitrosylase NOS1,NOS1抗体 |
| Swissprot | P29475,P29476,Q9Z0J4 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse nNOS |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:300-1:800; |
| Concentration | 350 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cell projection, Membrane |
| Tissue specificity | Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.Highest expression level in vastus lateralis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene. |
Images
Western Blot analysis of various samples using NOS1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Human brain cancer using NOS1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Mouse brain using NOS1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using NOS1 Polyclonal Antibody at dilution of 1:300.
