p19 INK4d Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Hela,HepG2,A431,Human liver,Human stomach cancer,Mouse spleen,Mouse testis,Rat spleen,Rat testis |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse p19 INK4d |
| Abbre | p19 INK4d |
| Synonyms | CDK inhibitor p19INK4d;CDKN2D;Cyclin dependent kinase inhibitor 2D;Cyclin-dependent kinase 4 inhibitor D;Cyclin-dependent kinase inhibitor 2D (p19; inhibits CDK4);inhibitor of cyclin-dependent kinase 4d;INK4D;MGC109660;MGC137547;MGC73010;p19;p19-INK4D;p19INK4d;Similar to cyclin-dependent kinase inhibitor 2D抗体 |
| Swissprot | |
| Calculated MW | 19kDa |
| Observed MW | 19kDa |
| Cellular Localization | Cytoplasm, Nucleus |
| Concentration | 2.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer;Cell Biology;Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. |
Western Blot analysis of various samples using p19 INK4d Polyclonal Antibody at dilution of 1:500.
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
