PARD3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Rat brain |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Rat Partitioning defective 3 homolog protein |
| Abbre | PARD3A |
| Synonyms | agouti signaling protein;ASIP;Atypical PKC isotype specific interacting protein;Atypical PKC isotype-specific-interacting protein;Baz;bazooka;Coagulation factor II receptor-like 2;CTCL tumor antigen se2-5;F2rl2;PAR-3;par-3 family cell polarity regulator alpha;par-3 family cell polarity regulator;PAR3 alpha;par3;PAR3-alpha;PARD-3;Pard3;PARD3;PARD3A;Partitioning defective 3 homolog;Partitioning-defective 3 homolog;Partitioning-defective protein 3;C. elegans;homolog of;SE2-5L16;SE2-5LT1;SE2-5T2;Thrombin receptor-like 2抗体 |
| Swissprot | |
| Calculated MW | 151 kDa |
| Observed MW | 151 kDa |
| Cellular Localization | Endomembrane system. Cell junction. Cell junction>tight junction. Cell membrane. Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. Localized along the cell-cell contact region. Colocalizes with PARD6A and PRKCI at epithelial tight junctions. Colocalizes with the cortical actin that overlays the meiotic spindle during metaphase I and metaphase II (By similarity). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. |
| Concentration | 2 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Neuroscience; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.PARD3 (Par-3 Family Cell Polarity Regulator) is a Protein Coding gene. Diseases associated with PARD3 include Gamma Heavy Chain Disease and Enamel Caries. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Ras signaling pathway. GO annotations related to this gene include protein phosphatase binding and phosphatidylinositol-4,5-bisphosphate binding. An important paralog of this gene is PARD3B. |
Western Blot analysis of Rat brain tissue using PARD3A Polyclonal Antibody at dilution of 1:500
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
