PAX5 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human prostate cancer,Human esophagus cancer |
Dilution | IHC 1:30-1:150 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human PAX5 |
Abbre | PAX5 |
Synonyms | B cell lineage specific activator;B cell lineage specific activator protein;B cell specific activator protein;B cell specific transcription factor;B-cell-specific transcription factor;BSAP;EBB-1;KLP;Paired box 5;Paired box gene 5 (B cell lineage specific activator protein);Paired box gene 5 (B cell lineage specific activator);Paired box gene 5;Paired box homeotic gene 5;Paired box protein Pax 5;Paired box protein Pax-5;Paired domain gene 5;PAX 5;PAX5;PAX5;Transcription factor PAX 5抗体 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 0.84 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Neuroscience |
Conjugation | Unconjugated |
Background | PAX5,also named B-cell specific activator protein (BSAP),is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B,pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL,PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members. |
Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using PAX5 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PAX5 Polyclonal Antibody at dilution of 1:30(×200)
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