PAX6 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IF
Verified Samples |
Verified Samples in IF: U-2OS |
Dilution | IF 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant fusion protein of human PAX6 (NP_000271.1). |
Abbre | PAX6 |
Synonyms | AN;AN2;ASGD5;D11S812E;FVH1;MGDA;WAGR;PAX6抗体 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 1mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Neuroscience; Stem Cells |
Conjugation | Unconjugated |
Background | This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. |
Immunofluorescence analysis of U-2 OS cells using PAX6 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.