PFKFB3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB:293T,A549,A431,Hela,Jurkat |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human PFKFB3 |
Abbre | PFKFB3 |
Synonyms | Renal Carcinoma Antigen NY-REN-56;PFK/FBPase 3;IPFK2;PFK2抗体 |
Swissprot | |
Calculated MW | 60 kDa |
Observed MW | Refer to figures |
Concentration | 0.9 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cardiovascular;Signal Transduction;Neuroscience;Cancer;Metabolism |
Conjugation | Unconjugated |
Background | The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Western blot analysis of 293T A549 A431 Hela and Jurkat cell lysates using PFKFB3 Polyclonal Antibody at dilution of 1:400
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E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |