PHF21A Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:293T,Hela,A375 Verified Samples in IHC:Human prostate cancer,Human esophagus cancer |
| Dilution | WB 1:500-1:2000;IHC 1:40-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human PHF21A |
| Abbre | PHF21A |
| Synonyms | BHC80a;BM-006;BRAF35-HDAC complex protein BHC80;BRAF35/HDAC2 complex (80 kDa);KIAA1696;PF21A;PHD finger protein 21A;PHF21A抗体 |
| Swissprot | |
| Calculated MW | 75 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. |
| Concentration | 0.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling; Neuroscience |
| Conjugation | Unconjugated |
| Background | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events. |
Western blot analysis of 293T Hela and A375 cell lysates using PHF21A Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using PHF21A Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PHF21A Polyclonal Antibody at dilution of 1:50(×200)
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
