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PRKAG2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human PRKAG2
Abbre
PRKAG2
Synonyms
5''-AMP-activated protein kinase subunit gamma-2;AAKG;AAKG2;AAKG2;AMPK gamma2;AMPK subunit gamma 2;AMPK subunit gamma-2;CMH6;H91620p;Prkag2;Protein kinase AMP activated gamma 2 non catalytic subunit;WPWS抗体
Swissprot
Cellular Localization
Cytosol,Extracellular region or secreted,extracellular space,Nucleus,nucleoplasm,Other locations:nucleotide-activated protein kinase complex
Concentration
0.96 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cardiovascular; Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. PRKAG2 (Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2) is a Protein Coding gene. Diseases associated with PRKAG2 include Glycogen Storage Disease Of Heart, Lethal Congenital and Wolff-Parkinson-White Syndrome. Among its related pathways are RET signaling and Regulation of TP53 Activity. GO annotations related to this gene include protein kinase binding and protein kinase activator activity. An important paralog of this gene is PRKAG1.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PRKAG2 Polyclonal Antibody at dilution of 1:55(×200)


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