PRMT5 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:K562,Hela,293T |
| Dilution | WB 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human PRMT5 |
| Abbre | PRMT5 |
| Synonyms | 72 kDa ICln binding protein;72 kDa ICln-binding protein;ANM5;Histone synthetic lethal 7;S. cerevisiae;homolog of;Histone-arginine N-methyltransferase PRMT5;HMT1 hnRNP methyltransferase like 5;HOMOLOG OF;SKB1;HRMT1L5;IBP72;Jak-binding protein 1;JBP 1;JBP1;PRMT 5;PRMT5;Protein arginine methyltransferase 5;Protein arginine N methyltransferase 5;Protein arginine N methyltransferase 5 N terminally processed;Protein arginine N-methyltransferase 5;S. POMBE;S. POMBE HOMOLOG OF;SKB1;SHK1 KINASE BINDING PROTEIN 1;Shk1 kinase binding protein 1 homolog;Shk1 kinase-binding protein 1 homolog;Shk1 kinase/binding protein 1;S. pombe;homolog of;SKB 1;SKB1;SKB1 homolog;SKB1: SKB1 homolog (S. pombe);SKB1Hs抗体 |
| Swissprot | |
| Calculated MW | 71kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. |
Western Blot analysis of K562, hela and 293T cell using PRMT5 Polyclonal Antibody at dilution of 1:400
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
