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PTPA Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human ovarian cancer,Human thyroid cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human PTPA
Abbre
PTPA
Synonyms
subunit B'';KIAA0044 ;MGC2184 ;Phosphotyrosyl phosphatase activator;PP2A;PP2A phosphatase activator ;PP2A subunit B';PP2A subunit B' isoform PR53;PP2A subunit B' PR53 isoform ;PPP2R4;PR53 ;PR53 isoform;Protein phosphatase 2; regulatory subunit B-prime;Protein phosphatase 2A activator regulatory subunit 4;Protein phosphatase 2A regulatory subunit B' (PR 53);PTPA;PTPA;Serine/threonine protein phosphatase 2A regulatory subunit B' ;Serine/threonine-protein phosphatase 2A activator;Serine/threonine-protein phosphatase 2A regulatory subunit 4;Serine/threonine-protein phosphatase 2A regulatory subunit B''抗体
Swissprot
Cellular Localization
Cytoplasm. Nucleus.
Concentration
1.08 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal transduction
Conjugation
Unconjugated
Background
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(×200)


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