Purified Anti-Human CD45 Antibody[HI30]
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
Alternate Names | Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | Unconjugated |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |