Recombinant Human ASB13 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： Q8WXK3
| 别称 |
Ankyrin repeat and SOCS box protein 13;ASB13;
|
| 表达系统 |
E.coli
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| 序列 |
Met 1-Asn278
|
| 蛋白编码 |
Q8WXK3
|
| 种属 |
Human
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| 计算分子量 |
31.4 kDa
|
| 表观分子量 |
28 kDa
|
| 标签 |
N-His
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 4M Urea, pH 7.4.
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| 复溶方法 |
Not Applicable
|
| 背景 |
Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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实验操作视频
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