Recombinant Human Ephrin B Receptor 1/EphB1 (C-Fc)
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- 表达系统： HEK293 Cells
- 蛋白编码： P54762
| 别称 |
Ephrin Type-B Receptor 1;ELK;EPH Tyrosine Kinase 2;EPH-Like Kinase 6;EK6;hEK6;Neuronally-Expressed EPH;Related Tyrosine Kinase;NET;Tyrosine-Protein Kinase Receptor EPH-2;EPHB1;ELK;EPHT2;HEK6
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| 表达系统 |
HEK293 Cells
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| 序列 |
Met18-Pro540
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| 蛋白编码 |
P54762
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| 种属 |
Human
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| 计算分子量 |
85.6 kDa
|
| 表观分子量 |
85-110 kDa
|
| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
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实验操作视频
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