Recombinant Human IL10RB/IL10R2 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q08334
| 别称 |
CDW210B;CRF2-4;CRFB4;D21S58;D21S66;IL-10R2;Interleukin-10 receptor subunit beta(IL10RB);Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;Interleukin-10 receptor subunit 2
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| 表达系统 |
HEK293 Cells
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| 序列 |
Met20-Ser220
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| 蛋白编码 |
Q08334
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| 种属 |
Human
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| 计算分子量 |
24.5 kDa
|
| 表观分子量 |
48 kDa
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| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
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实验操作视频
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