Recombinant Human WISP1 protein (His tag)
Price:
- 表达系统: HEK293 Cells
- 蛋白编码: O95388
别称 |
CCN family member 4;WNT1-inducible-signaling pathway protein 1;WISP-1;Wnt-1-induced secreted protein;WISP1;CCN4
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表达系统 |
HEK293 Cells
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序列 |
Met1-Asn367
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蛋白编码 |
O95388
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种属 |
Human
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计算分子量 |
40.3 kDa
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表观分子量 |
60 kDa
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标签 |
C-His
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纯度 |
> 95 % as determined by reducing SDS-PAGE.
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内毒素 |
Please contact us for more information.
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保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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制剂 |
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.
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实验操作视频
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