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RHOB Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB:Mouse brain,Mouse fetal brain
Dilution
WB 1:1000-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human RHOB
Abbre
RHOB
Synonyms
Aplysia RAS-related homolog 6;ARH6;ARHB;H6;MST081;MSTP081;oncogene RHO H6;ras homolog family member B;ras homolog gene family;member B;Rho cDNA clone 6;Rho related GTP binding protein RhoB Precursor;Rho-related GTP-binding protein RhoB;Rhob;RHOB;RHOH6抗体
Swissprot
Calculated MW
22kDa
Cellular Localization
Late endosome membrane. Cell membrane. Nucleus. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Signal Transduction
Conjugation
Unconjugated
Background
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Western Blot analysis of Mouse brain and fetal brain tissue using RHOB Polyclonal Antibody at dilution of 1:800
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